Cuticlin: Contraindications, Properties And Benefits

We know that the adolescent stage can be complicated a bit thanks to the different hormonal changes, various conditions can occur, one of these evils can be effectively treated with Cuticlin. An effective solution for those young people between 12 and 18 years of age, who are affected by the annoying pimples, pimples or blackheads , generally known as acne.

It is a common problem , that fat that can block pores and cause small inflammations that appear in places such as the back, chest, face, neck or arms. Although it is more common in young people, it can also affect some people in adulthood. It is common for them to cause spots where they appear, especially in the area of ​​the face.

When this happens, it is normal for us to seek help and that is where Cuticlin acts, it is presented as one of the most recommended treatments by dermatologists worldwide; is an effective product in the fight against this condition or disease

Here we leave you all the information you should know about this highly marketed and very useful product for treating acne-related conditions.

What is Cuticlin?

Cuticlin or Isotretinoin is a specialized medicine for systemic use, which acts in the elimination of severe acne and in mild cases, that is, Cuticlin suppresses the activity generated by the sebaceous glands, in addition to considerably reducing their size. It is one of the products that has shown the best results as a treatment against this problem.

Generally, most Cuticlin treatments have a maximum time of up to 6 months and a minimum of 3 months; according to the majority of cases that have been registered. Mild conditions treatment with Cuticlin requires less time. It will be the dermatologist who will adapt a dose for you , depending on the severity of your case.

Much more on this topic with  Severe Acne: Treatments, Pathologies, Symptoms and Causes.

Cuticlin additional names

Like many medicinal products, Cuticlin can be found in various forms and under other names , the most common being Isotretinoin.

Are there products similar to Cuticlin?

If we look for this treatment and we do not find it with either of the two most common names (Cuticlin or Isotretinoin), we can also find similar drugs that have the same medicinal properties and uses.

Among these we can find other products such as:  isotrex, oratane, retinoral, isoface, isotriderm, roaccutan, acnotin, acnemin, dercutane, farmacné, flexresan, isdiben, mayesta, isoacné, hynriax or liascne. These are the most prominent similar products.

Origin of Cuticlin

Trying to find the cure or treatment that reduces the appearance of acne is a constant task for a long time. In the 1930s, one of the first drugs used was retinoic acid, commonly known as vitamin A. This was used in doses that were too high to be able to obtain obvious results.

Due to this it was discovered that it can inhibit the production of sebum to levels that are toxic. Originally, the retinoic acid derivative isotretinoin (Cuticlin) was developed by Hoffman-La Roche in 1982 , but Dr. Gary Peck is credited with discovering its use in skin conditions such as cystic acne and others .

Hoffman-La Roche was responsible for distributing this drug under its Accutane brand in the United States. In February 2002 Roche’s patent expired and since then several cheap generic versions of this product have been distributed by different drug companies.

By June 29, 2009, Roche officially discontinued the manufacture and distribution of the brand, due to the low market share of this presentation of the drug. However, generic Cuticlin or Isotretinoin continues to be distributed through various manufacturing companies.

For more information on this topic, we invite you to read  Isotretinoin: Contraindications, Properties and Benefits

It is a drug that has had ups and downs since its discovery, especially since its application to cure skin conditions began. It was originally used to treat only severe acne, but today it is used in different cases of mild acne. In addition, drug organizations are increasingly joining as distributors.

What are the ingredients in Cuticlin?

Cuticlin is a drug that is composed of various ingredients in each commercial presentation, which are two: soft and hard capsules. Here we leave you a list with all these components of each one, which are part of the elaboration of this product.

Each Cuticlin softgel contains:

  • The active substance in Cuticlin is isotretinoin.
  • Yellow beeswax.
  • Partially hydrogenated soybean oil.
  • Hydrogenated soybean oil.
  • Refined soybean oil.
  • Refined Shellac.
  • Cantaxanthin E161.
  • Black iron oxide E172.
  • Titanium dioxide E171.

Each Cuticlin hard capsule contains the following excipients:

  • Stearoyl macroglycerics (Gelucire 50/13).
  • Yellow iron oxide E172.
  • Titanium dioxide E171.
  • Refined soybean oil.
  • Sorbitan oleate.
  • Indigocarmine E132.

Where to buy Cuticlin?

Cuticlin or Isotretinoin is available almost everywhere in the world , you can find it in pharmacies and the like. It is important to note that for its acquisition you necessarily need a medical prescription.

You can also find it online , there are countries where the prescription is not necessary (which are becoming more and more) and only they can distribute it in this way. This may become a problem for people who reside in countries where the pharmaceutical industry is highly regulatory , if this is your case, it is best to go to the doctor.

In Spain, although it is not a country as restricted with this drug as in other regions, Cuticlin can only be prescribed by dermatologists and a prescription is necessary to obtain it.

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Does Cuticlin Really Work?

Pharmacists and dermatologists who prescribe it will always answer yes, because it really works . This can be verified through numerous cases where Cuticlin was highly effective in eliminating those annoying pimples, pimples or blackheads.

Are there cases where the Cuticlin did not work ?, yes, there are few cases where it did not work totally, but people saw certain improvements. Despite this, the percentage is not significant and therefore it is argued that Cuticlin is a fully functional drug .

What I should know about Cuticlin: Importance

Many wonder what exactly should I know about Cuticlin? The best advice we can give you is to find all the information related to this medicine before using it . There is nothing better than having all the knowledge about any medication that we will use, especially of this type to avoid health problems later.

You must be aware of all the basic information, the conditions of your case, if you can use it, what is Cuticlin, compounds that comprise it, benefits, warnings, side effects, among others. Make sure you have all this information.

Cuticlin benefits

Cuticlin was developed with the best compounds to help clear up acne. Mostly for the treatment of severe acne cases with inflamed pimples and unpleasant blackheads. That is why it is considered as the main benefit of Cuticlin.

In addition, Cuticlin has the ability to leave your skin extremely soft and smooth . It is also an anti-inflammatory par excellence, it reduces the production of natural oil in our skin (the ones that cause those pimples). Also, it reduces inflammation and avoids the risk of permanent scars .

Cuticlin has components that help a little in cases of hidradenitis suppurativa, to treat harlequin ichthyosis, lamellar ichthyosis, xeroderma pigmentosa and keratosis . Additionally, this product has been used to treat very rare conditions such as fibrodysplasia ossificans progressiva and neuroblastomas (which is a nerve cancer).

Check in this article  Why do pimples appear, Remedies and How to avoid them

Before using Cuticlin, what can I ask my doctor?

Before using it, you should strictly ask your doctor about the convenience or not of the drug. It is not optional, you must do it. The dose you are going to ingest will depend on different factors such as your weight, medical condition and degree of acne, among others. You should consult a specialist about the appropriate dose and duration of treatment according to your case.

As for what to ask the doctor, through the development of the article, we answer some of the most frequent questions, in addition to our recommendation based on facts and demonstrations.

How to use Cuticlin?

There is only one way to use Cuticlin and that is by ingesting it. Many patients claim to squeeze the softgels and use them directly on the skin , but don’t do it because Cuticlin doesn’t work this way. There are also those who might tell you that it is used to treat other conditions (which do not have to do with the skin), but the possible effects of the drug in other types of conditions have not been proven.

It is a medication only and strictly for the treatment of acne . Don’t use it lightly, simply because you heard a friend use it or saw it at the pharmacy and it caught your eye. You must know in advance its composition, benefits and adverse effects before using it.

How is Cuticlin ingested?

Cuticlin can be found only in capsules (whether soft or hard), the first thing you must have to ingest this drug is a medical prescription, only a health specialist can tell you the appropriate dose. You can ingest it at any time of the day normally, orally. We recommend doing it after eating and accompanying it with a drink, preferably water.

Check our article on  Tetralysal: Contraindications, Properties and Benefits

In case of missing a dose of Cuticlin, what happens?

What should I do or not do if I forget to take a dose? The first thing is that you should not make up for this forgotten dose . If it’s just one dose, you won’t have much trouble catching up. You should only take Cuticlin as soon as possible, as long as you continue with the treatment as directed by the specialist.

You should never take a missed dose with the next one. If you stop taking several doses or for a considerable period of time (1 month or more) you should go to the doctor again. Don’t try to pick up where you left off.

In case of overdose with Cuticlin, what should I do?

If you exceed the prescribed dose of Cuticlin, the first thing you should do is immediately consult the doctor who prescribed this medication. In the most serious cases, of overdose or accidental extreme intake, it will be necessary to go directly to the nearest clinic and state the case, do not forget to give all the details related to the drug.

Since your health will depend on that, even life. The best thing is that they contact your doctor from the clinic and with his help they can treat the overdose . These things do not usually happen by mistake, it is a drug that can be toxic, and you will surely know it from the beginning.

With which drugs does the use of Cuticlin interact or are not recommended?

Before trying to use Cuticlin, you should inform your doctor about other treatments that you are taking, even those that are of natural origin. It is because the compounds in these could interact negatively with the new drug.

Do not take vitamin supplements for any reason, that is, vitamin A, or antibiotics (tetracyclines) while you are using Cuticlin; the combination of both could cause great risks.

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Optically supplied keratolytic or exfoliative preparations cannot be used , as these can cause increased local irritation. Many dermatologists recommend that minerals such as zinc be ingested, they have no longer been shown to cause adverse effects.

If I am taking Cuticlin, what should I avoid?

The main thing is to avoid getting pregnant , it is strictly necessary. This restriction is always reminded to patients. You should also avoid exposure to the sun, this can have several negative effects. You can take medications that contain compounds that do not interact with Cuticlin.

Does Cuticlin affect pregnant women?

Yes, Cuticlin severely affects pregnant women . This condition is in itself an absolute contradiction. For women on the treadmill, this medicine poses a risk. The story between pregnant women and the main ingredient in Cuticlin (Isotretinoin) has several antecedents.

Between 1982 and 2003, more than 1,500 American women who became pregnant while using this product ended up undergoing an abortion (some even induced). There were also many cases of babies born with serious congenital defects or malformations.

This led the US FDA to induce the ¡PLEDGE program, which attempts to ensure that patients (women) who consume this drug are not or become pregnant. Although there is no evidence that this product is excreted through seminal fluids, this program was also applied in men.

With these historical data and laws established for Cuticlin, it is very clear that pregnant women should not ingest this drug as it terribly affects the fetus , they are also affected. It does not hurt that you consult your doctor and he verifies this information. Also, there is no evidence regarding the drug’s effects on fertility.

Read the article we have on  Chemical Pregnancy: Problems, Signs, Duration, Symptoms and Causes

What should you do if you are taking Cuticlin and think you are pregnant?

The first thing you should do when you think you are pregnant is consult your doctor about this and any other medication. The case of Cuticlin is no exception, you must stop consuming the product immediately due to the risks that it represents for the fetus and visit the doctor immediately to inform him.

It will be the doctor who will indicate what to do if the pregnancy test is positive, since this medicine should be stopped at least one month before trying to get pregnant. So if you are taking Cuticlin and you think you may be expecting a baby, you should have the treatment as soon as possible.

Is it safe to breastfeed while using Cuticlin?

Cuticlin is also forbidden to ingest while breastfeeding . It is because the little ones receive all the nutrients from the mother by this means and the medicine can pass into the milk if you consume it. Do not take it during and after pregnancy, at least during the first year. You can consult your doctor about this restriction if you wish.

Precautions and adverse effects on the intake of Cuticlin

Like any processed or natural medicine, taking Cuticlin can cause various adverse effects. These contraindications can be of two types, from the strongest to the least serious, here we leave you all the contraindications in detail.

Serious adverse effects from consuming Cuticlin

These serious effects or contraindications usually occur very little , the cases are isolated in relation to the use of Cuticlin. They are usually given by excessive dose, that is, overdose; allergy to the product or any reaction to any of the components of the drug.

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Uncontrolled intake of Cuticlin can lead to negative thoughts in the user , of harming himself or killing himself. Many patients show signs of depression after having finished the medicine or a worsening of it, they may even develop other mental problems.

Among the rarer and psychiatric symptoms are: proneness to sadness, anxiety, insomnia, irritability, excessive crying, changes in mood, loss of appetite, loss of interest in sports or social activities, decrease in school performance or cause problems at work as it can influence concentration.


The reasons why you may have an allergic reaction are different and these will depend on your body, the common symptoms are: persistent tightness in the chest (difficulty breathing) especially in asthmatic people, skin rashes that burn and cause itching. In these cases, treatment must be completely suspended.

Other general symptoms of allergic reactions are usually : asthma attack, shortness of breath, wheezing or very rapid breathing, sudden swelling of the face or tongue, affections on the vocal cords, hives, itching, paleness, skin rashes or loss of consciousness.


These effects include: Excessive thirst, constant urge to go to the bathroom, significant increase in blood sugar levels (which could become diabetes), it is very important that you are aware of these and all the contradictions during treatment with Cuticlin.


These cases are the least common on our list , mostly when Cuticlin is administered with other medications (such as antibiotics). They usually cause: Increased intracranial pressure, drowsiness and even seizures . And the most common symptoms are nausea, dizziness, vomiting, blurred vision, among others.

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Taking this medicine can cause inflammation in the pancreas (known as pancreatitis), gastrointestinal bleeding, intestinal inflammation, colitis, abdominal pain, or severe diarrhea (accompanied by blood or vomiting).


The registered cases where Cuticlin has affected the liver are minimal. But if you see that your eyes are turning very yellow and your body feels very tired, your consumption may have caused you hepatitis .


The most common renal reaction or adverse effect from the consumption of this product is inflammation of the kidneys (glomerulonephritis). Among the most visible symptoms are: excessive fatigue, cessation of urine, swollen eyelids, among others.

Non-serious adverse effects of Cuticlin

When we talk about these non-serious adverse effects or mild contraindications, we refer to those that occur more frequently and are easier to treat, comparing these with the serious ones. There are several cases of this nature registered by ingesting Cuticlin. They usually occur as a result of a reaction and here we tell you which are the most common.


A side effect of consuming Cuticlin is dry skin, generally in areas such as the lips, which tend to split, and the face with slight peeling, severe itching, a rash (affected area) or inflammation of the same. We recommend using a moisturizing product regularly from the beginning of the treatment to avoid these effects.

It can also affect the eyes , you can start to feel tired and a little irritated. You must avoid dermabrasion by all means, that is, remove calluses and scabs that appear and wax. These symptoms are generally reversible once treatment is finished .

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A very common symptom is back pain (low back pain), pain in the joints or in the muscles themselves. You should try to decrease your physical activities with intensity during the consumption of Cuticlin . These adverse effects are also reversible upon completion of treatment.


This only happens in the first few weeks, it is very likely that the acne will get worse on its own instead of getting better . However, this should stop happening for at least the fifth week and begin to improve afterwards. So do not worry the first time and wait for the advances of the Cuticlin treatment.

Other adverse effects

  • Sweating excessively
  • Photo-sensitivity to sunlight, we recommend you start using sunscreen.
  • Very rarely, the ability to distinguish colors.
  • Corneal opacities.
  • Alterations that produce arthritis or tendon pain.
  • Infections in the tissues around the nails.
  • Swelling in various areas of the body.
  • Problems with the scalp, usually the loss and very rare the increase.
  • Increased facial pigmentation or high levels of body hair growth.
  • Decrease in white blood cells in our body.
  • Swelling of the lymph nodes.
  • Considerably slow down the clotting process.
  • Abnormal levels in the known blood of urea, liver enzymes or sugar.
  • Disorders in various substances, commonly such as proteins or blood cells excreted in the urine.
  • Abnormalities in blood levels of different substances (such as cholesterol or triglycerides).
  • Aggressive and violent behavior.
  • Headache and blurred vision.
  • Hemorrhage (bleeding from the nose).

Cautions and warnings

  • If you are allergic or hypersensitive to its active principle (Isotretinoin) or any of its components, you should avoid the product.
  • If you suffer from insufficiency (especially liver).

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  • If you have high levels of lipids before starting treatment (cholesterol, triglycerides).
  • If you have very high levels of vitamin A in the body.
  • If you are taking tetracyclines, that is, an antibiotic.
  • If you suffer from a high type of mental disorder (such as depression).
  • For no reason can you donate blood, not a couple of months after stopping the drug.
  • Be very careful to those who suffer from kidney failure or liver problems.
  • Completely avoid the use of exfoliative creams or ointments that are for topical use, especially if they are not prescribed by a doctor.
  • If you suffer from conditions such as diabetes, obesity or alcohol addiction, in these cases it is vitally important to establish controls with the doctor.

In summary, Cuticlin is a drug that treats acne in a severe, fast and effective way, that you should try to try if you present those annoying conditions such as pimples, blemishes, blackheads, blackheads or pimples; especially on the face. These adverse effects and contradictions should not scare you, you simply must be aware of the possible risks before using it, it is a controllable product.

As long as you pay attention to the precautions and warnings, it is a drug that should not be considered lightly and its use should be under the strict supervision of a dermatologist . It is better to be safe than sorry, you do not lose anything by asking if you can use it or other doubts you have regarding the drug.

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Kathie Sand always saw the world of beauty as the terrain on which to build her professional career, a goal that was clear to her when she was only 15 years old. Her great concern to expand knowledge led her to settle in Paris where she studied hand in hand with the best beauty professionals and with the most advanced techniques for skin care.

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